Why is ApoB considered a superior marker for cardiovascular risk compared to LDL-C?
ApoB is a superior marker for cardiovascular risk because it quantifies the number of atherogenic particles capable of initiating plaque formation, rather than just the cholesterol content per particle. Studies have shown that a significant percentage of individuals with normal LDL-C levels can still have elevated ApoB, indicating a risk misclassification if only LDL-C is measured.
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