Q

How does isotretinoin work as an acne treatment?

From 5 years of verified research · Vassili Sandqvist
A

Isotretinoin is the most effective acne treatment available, as it reduces sebaceous gland size by 90%, dramatically decreases sebum output, eliminates C. acnes, and normalizes keratinization. Due to its teratogenicity and the need for monitoring, it is reserved for severe nodular acne.

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