How does naltrexone work in the treatment of alcohol use disorder?
Naltrexone acts as an opioid receptor antagonist, blunting the rewarding effects of alcohol by blocking opioid receptors. This reduces the neurochemical reward associated with drinking, leading many patients to report that alcohol loses its pleasurable taste.
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This is one answer. The complete system — the psychology, the biology, and the method — is in the book.
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