Q

How does Irving Kirsch's critique of antidepressants contribute to the discussion?

From 5 years of verified research · Vassili Sandqvist
A

Irving Kirsch's analysis highlighted that the drug-placebo difference in symptom score reduction is not clinically significant for mild-to-moderate depression, with meaningful effects primarily seen in severe cases. This critique does not negate the efficacy of antidepressants; rather, it clarifies that their benefits are most pronounced in severe depression.

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