Q

What are the physiological barriers that can prevent weight loss despite a caloric deficit?

From 5 years of verified research · Vassili Sandqvist
A

Physiological barriers include conditions like hypothyroidism, polycystic ovary syndrome (PCOS), obstructive sleep apnea, and certain medications. Each of these can disrupt metabolic processes or hormonal balance, making it difficult to achieve expected weight loss outcomes. For instance, untreated hypothyroidism can significantly lower your total daily energy expenditure.

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