Q

How is vitamin D synthesized in the body?

From 5 years of verified research · Vassili Sandqvist
A

Vitamin D3, or cholecalciferol, is synthesized in the skin from 7-dehydrocholesterol upon exposure to UVB radiation. This compound is then converted in the liver to 25(OH)D, the circulating form, and further transformed in the kidneys to 1,25(OH)2D, or calcitriol, which is the biologically active form that interacts with various tissues.

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