How does sleep deprivation affect the immune system?
Sleep deprivation is the highest-impact modifiable factor that suppresses immune function. Research indicates that individuals who sleep fewer than 6 hours are 4.2 times more likely to catch a cold when exposed to rhinovirus compared to those who get 7 or more hours. Chronic sleep restriction diminishes cytokine production, natural killer cell activity, and T-cell proliferation, all crucial for a robust immune response.
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