Q

How does insulin contribute to muscle protein synthesis?

From 5 years of verified research · Vassili Sandqvist
A

Insulin plays a permissive and additive role in muscle protein synthesis by activating the PI3K-Akt pathway, which signals mTORC1 alongside leucine. This means that insulin, in conjunction with amino acids, enhances the net protein balance in muscle, making it essential for optimal recovery and growth.

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